Journal of Cancer Research and Therapeutics

ORIGINAL ARTICLE
Year
: 2010  |  Volume : 6  |  Issue : 1  |  Page : 15--21

Prospective subjective evaluation of swallowing function and dietary pattern in head and neck cancers treated with concomitant chemo-radiation


Jaiprakash Agarwal1, Debnarayan Dutta1, Vijay Palwe1, Tejpal Gupta1, Sarbani Ghosh Laskar1, Ashwini Budrukkar1, Vedang Murthy1, Pankaj Chaturvedi2, Prathemesh Pai2, Devendra Chaukar2, AK D'Cruz2, Suyesh Kulkarni3, Aniruddh Kulkarni3, Gurmit Baccher4, Shyam Kishor Shrivastava1 
1 Department of Radiation Oncology, Tata Memorial Hospital, Mumbai, India
2 Department of Surgical Oncology, Tata Memorial Hospital, Mumbai, India
3 Department of Interventional Radiology, Tata Memorial Hospital, Mumbai, India
4 Department of Speech Therapy, Tata Memorial Hospital, Mumbai, India

Correspondence Address:
Jaiprakash Agarwal
Department of Radiation Oncology, Tata Memorial Hospital, Mumbai
India

Aim : Prospective subjective evaluation of swallowing function and dietary pattern in locally advanced head and neck cancer patients treated with concomitant chemo-radiotherapy (CRT). Materials and Methods : Prospective evaluation of swallowing function with performance status scale for head and neck cancer patients (PSSHN) at pre-CRT, CRT completion and at subsequent follow-ups in adult with loco-regionally advanced head and neck squamous cell carcinoma (HNSCC) patients. Results : In 47 patients (40 male, seven females; mean age 53; 72% smoker 53%, oropharyngeal cancer), the mean total PSSHN score at pre-CRT was 258.5 and decreased to 225.2 and 219.2 at two and six months respectively. Understandability of speech, normalcy in diet and eating in public at pre-CRT and six months were 91.5 and 84.4; 80.4 and 63.1; 87.3 and 76.6 respectively. In univariate analysis, pre-CRT PSSHN scores were significantly lesser in patients with severe pre-CRT dysphagia (P = 0.001), hypopharyngeal cancer (P = 0.244) and advanced T-stage (T3/4) disease (P = 0.144). At CRT completion, there was significant reduction of PSSHN scores in patients with severe pre-CRT dysphagia (P = 0.008), post-CRT weight loss (>10%) and disease progression (P = 0.039). At two months and six months, 17 (57%) and 11 (73.5%) patients respectively showed change in dietary habit. Mean increase in meal time was 13% and 21% at two and six-month follow-up. Conclusions : HNSCC patients show deterioration in swallowing function after CRT with normalcy of diet in maximum and eating in public least affected. Pre-CRT severity of dysphagia, weight loss >10% and disease progression have significant correlation with higher swallowing function deterioration after CRT.


How to cite this article:
Agarwal J, Dutta D, Palwe V, Gupta T, Laskar SG, Budrukkar A, Murthy V, Chaturvedi P, Pai P, Chaukar D, D'Cruz A K, Kulkarni S, Kulkarni A, Baccher G, Shrivastava SK. Prospective subjective evaluation of swallowing function and dietary pattern in head and neck cancers treated with concomitant chemo-radiation.J Can Res Ther 2010;6:15-21


How to cite this URL:
Agarwal J, Dutta D, Palwe V, Gupta T, Laskar SG, Budrukkar A, Murthy V, Chaturvedi P, Pai P, Chaukar D, D'Cruz A K, Kulkarni S, Kulkarni A, Baccher G, Shrivastava SK. Prospective subjective evaluation of swallowing function and dietary pattern in head and neck cancers treated with concomitant chemo-radiation. J Can Res Ther [serial online] 2010 [cited 2020 Sep 19 ];6:15-21
Available from: http://www.cancerjournal.net/article.asp?issn=0973-1482;year=2010;volume=6;issue=1;spage=15;epage=21;aulast=Agarwal;type=0