Journal of Cancer Research and Therapeutics

BRIEF COMMUNICATION
Year
: 2007  |  Volume : 3  |  Issue : 3  |  Page : 167--168

Serum total glutathione-s-transferase levels in oral cancer


Krishnananda Prabhu, Gopalakrishna P Bhat 
 Department of Biochemistry, Kasturba Medical College, Manipal - 576 104, Karnataka, India

Correspondence Address:
Krishnananda Prabhu
Department of Biochemistry, Kasturba Medical College, Manipal
India

We conducted a study wherein serum total glutathione-s-transferase levels were measured in patients (n = 27) with various stages of biopsy proven oral cancer (squamous cell carcinoma) and age and sex matched healthy human volunteers (n=10). In all patients with oral cancer, serum total glutathione-s-transferase was measured before the onset of treatment. There was a significant increase in serum total glutathione-s-transferse levels in patients with stage IV oral cancer as compared to stage II (P = 0.001) and stage III (P = 0.002) oral cancer. This shows that alterations in serum total Glutathione-s-transferase levels may have a role in cancer progression.


How to cite this article:
Prabhu K, Bhat GP. Serum total glutathione-s-transferase levels in oral cancer.J Can Res Ther 2007;3:167-168


How to cite this URL:
Prabhu K, Bhat GP. Serum total glutathione-s-transferase levels in oral cancer. J Can Res Ther [serial online] 2007 [cited 2020 Aug 5 ];3:167-168
Available from: http://www.cancerjournal.net/article.asp?issn=0973-1482;year=2007;volume=3;issue=3;spage=167;epage=168;aulast=Prabhu;type=0