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Inflammatory myofibroblastic tumor of the oral cavity: A case report and literature review

1 Department of Oral Pathology and Microbiology, School of Dentistry, D. Y. Patil University, Mumbai, Maharashtra, India
2 Department of Oral Pathology and Microbiology, Nair Hospital Dental College, Mumbai, Maharashtra, India

Correspondence Address:
Subraj J Shetty,
Department of Oral Pathology and Microbiology, School of Dentistry, D. Y. Patil University, Sector 7, Nerul, Mumbai - 400 706, Maharashtra
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/jcrt.JCRT_1044_16

Inflammatory myofibroblastic tumor (IMT) is a rare tumor of unknown etiology and pathogenesis. The lesion has been recognized to occur at various sites but rarely affects the head and neck region. A 29-year-old male presented with a 13 months' history of a slow growing, painless growth in maxillary left posterior gingiva. An excisional biopsy was performed under local anesthesia. Microscopic examination revealed a compact cellular spindle cell proliferation with collagenous stroma having storiform architecture. Immunohistochemistry revealed that the tumor cells were positive for smooth muscle actin, CD-68 and negative for anaplastic lymphoma kinase. Oral IMT should be included in the differential diagnosis of localized gingival enlargement mimicking oral hyperplastic/reactive lesions.

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