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Noncirrhotic portal hypertension: An under-reported late adverse event of SIRT in metastatic colorectal cancer patients


1 Department of Medical Oncology, Hospital Universitario Puerta de Hierro-Majadahonda, Majadahonda, Madrid, Spain
2 Department of Vascular Radiology, Hospital Universitario Puerta de Hierro-Majadahonda, Majadahonda, Madrid, Spain
3 Department of Nuclear Medicine, Hospital Universitario Puerta de Hierro-Majadahonda, Majadahonda, Madrid, Spain
4 Department of Gastroenterology, Hospital Universitario Puerta de Hierro-Majadahonda, Majadahonda, Madrid, Spain
5 Department of Pathology, Hospital Universitario Puerta de Hierro-Majadahonda, Majadahonda, Madrid, Spain

Correspondence Address:
Lourdes Gutierrez,
Department of Medical Oncology, Hospital Universitario Puerta de Hierro-Majadahonda, Majadahonda, Madrid
Spain
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/jcrt.JCRT_1398_16

Introduction: Selective internal radiation therapy (SIRT) is increasingly used in different scenarios. Although portal hypertension (PHT) has been described as a nonclinically relevant finding after SIRT, its real incidence could have been neglected due to the nature of the diseases for which SIRT is indicated. Case Reports: Here we report three cases with clinically relevant late PHT after treatments including SIRT and oxaliplatin among others. Discussion: The sequential use of oxaliplatin and SIRT in patients with colorectal cancer metastases could have additive effects on the liver.


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    -  Gutierrez L
    -  Méndez S
    -  Mitjavila M
    -  Llop E
    -  Salas C
    -  Ruiz-Casado A
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