Home About us Editorial board Ahead of print Current issue Search Archives Submit article Instructions Subscribe Contacts Login 
 
REVIEW ARTICLE
Ahead of Print

PTEN and SHIP: Impact on lymphatic metastasis in breast cancer


1 Department of General Surgery, Hebei Yanda Hospital, Hebei, China
2 Department of General Surgery, Affliated Hospital of Taishan Medical University, Tai'an, China
3 Department of Gastroenterology, The Army General Hospital, Beijing, China
4 Department of Breast Surgery, Affliated Hospital of Taishan Medical University, Tai'an, China

Correspondence Address:
Xiang-qi Li,
Department of Breast Surgery, Affliated Hospital of Taishan Medical University, Tai'an 271000
China
Login to access the Email id

Source of Support: None, Conflict of Interest: None

Lymph node metastasis is the most common form of metastasis in breast cancer and a crucial indicator influencing breast cancer treatment results. The biological process of lymph node metastasis involves deficiency and mutation of tumor suppressor genes. PTEN and SHIP are critical indicators used to detect occurrence, development, invasion, and metastasis of breast cancer. Loss of expressions of PTEN and SHIP may contribute to lymphatic metastasis of breast cancer, so they can be used as objective indicators for judging the biological behavior of breast cancer. In this study, we perform a comprehensive analysis to investigate the effect of PTEN and SHIP gene expression on regulating lymph node metastasis in breast cancer.


Print this article
Search
 Back
 
  Search Pubmed for
 
    -  Li K
    -  Li Gd
    -  Sun Ly
    -  Li Xq
 Citation Manager
 Article Access Statistics
 Reader Comments
 * Requires registration (Free)
 

 Article Access Statistics
    Viewed233    
    PDF Downloaded9    

Recommend this journal