Does it matter if it is appendix mucocele instead of appendicitis? Case series and brief review of literature
Fatih Basak1, Mustafa Hasbahceci2, Metin Yucel1, Abdullah Sisik1, Aylin Acar1, Ali Kilic3, Meliha Seyma Su Dur4
1 Department of General Surgery, Health Science University, Umraniye Education and Research Hospital, Istanbul, Turkey
2 Department of General Surgery, Faculty of Medicine, Bezmialem Vakif University, Istanbul, Turkey
3 Department of General Surgery, Umraniye Education and Research Hospital, Istanbul, Turkey
4 Department of Radiology, Health Science University, Umraniye Education and Research Hospital, Istanbul, Turkey
Department of General Surgery, Health Science University, Umraniye Education and Research Hospital, Istanbul
Source of Support: None, Conflict of Interest: None
Aims: Appendiceal mucocele (AM) is a rare pathology, and its reported incidence is 0.3% in all appendectomy specimens. Here, we report a case series of AM and make a brief review of literature.
Subjects and Methods: We conducted a retrospective review of a prospectively collected data of patients who diagnosed as AM by histopathological evaluation between January 2009 and June 2015 were demographic data including age and gender, intraoperative findings, and histopathological reports were recorded. All cases were followed-up by routine examination and telephone interview.
Statistical Analysis Used: Definitive statistical methods (mean, standard deviation, median, frequency, and percentage) were used to evaluate the study data
Results: Twelve patients were examined in the study with diagnose of AM. The mean age was 51.8 ± 18.6 years (26–83). Female-to-male ratio was 1.4 (7/5). Indications for surgery were acute abdomen in 8 (72.7%) patients with presumptive diagnosis of acute appendicitis and were AM in four patients diagnosed by imaging. Histopathological evaluation revealed mucinous cystadenoma in eight patients, simple retention cysts in three, and borderline mucinous tumor (pseudomyxoma peritonei) in one. The neuroendocrine tumor was obtained on the remaining portion of the appendix in one of the simple retention cysts patients. None of the patients died because of the AM with an average follow-up of 43 months (range: 7–74).
Conclusions: Surgical resection is the first choice therapy for AM. Precise treatment modality can remain unclear in some patients because of insufficient preoperative diagnosis. It is nonmalign AM mostly however having mucocele matters because of the significant association with synchronous tumors.