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Renin-producing germ cell tumor in the pineal apparatus and mediastinum: A rare case report

 Department of Pulmonary Medicine, Fukushima Medical University School of Medicine, Fukushima 960-1295, Japan

Correspondence Address:
Hiroshi Yokouchi,
Department of Pulmonary Medicine, Fukushima Medical University School of Medicine, 1 Hikarigaoka, Fukushima 960-1295
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/0973-1482.180682

Ectopic extrarenal renin-producing tumor is a rare disease with approximately 30 case reports in English literature. We herein present the first case of renin-producing germ cell tumors in the pineal apparatus and mediastinum. A 26-year-old man who had undergone craniotomy for the treatment of pineal tumor was found to have hypertension at a regular visit postoperatively. Laboratory findings revealed high plasma levels of renin activity and that of aldosterone concentration. Chest computed tomography demonstrated a large tumor in the mediastinum. The pathological findings revealed the mediastinal germ cell tumor positive for renin. The present case suggests that for young patients presenting with hypertension with a mediastinal tumor, the possibility of a renin-producing tumor should be considered.

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