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CORRESPONDENCE
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Successful management of a patient with radiological presentation of choriocarcinoma syndrome before induction chemotherapy


 Department of Urology and Andrology, Graduate School of Medicine, Kansai Medical University, Osaka, Japan

Correspondence Address:
Hidefumi Kinoshita,
Department of Urology and Andrology, Graduate School of Medicine, Kansai Medical University, Osaka
Japan
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Source of Support: None, Conflict of Interest: None

Choriocarcinoma syndrome is a life-threatening lysis syndrome caused by blood vessel rupture and subsequent tumor bleeding. We describe a case of pretreatment choriocarcinoma syndrome that developed in a 27-year-old man. He underwent a high orchiectomy at a local hospital and was diagnosed with metastatic testicular tumor given the high serum human chorionic gonadotropin levels (943,601 mIU/mL). Thus, he was referred to our institution. Although he had bulky lung metastases and alveolar bleeding, we were able to administer full-dose chemotherapy with etoposide and cisplatin. On day 3 of chemotherapy, he presented with severe hypoxia and worsening of alveolar bleeding. Thus, he underwent tracheal intubation at the Intensive Care Unit. Full-dose chemotherapy was continued, and the patient was extubated upon improvement. He is currently alive and continuing treatment at another hospital.


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    -  Yoshida T
    -  Hayami Y
    -  Yoshida K
    -  Kinoshita H
    -  Matsuda T
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