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Primary mesenchymal chondrosarcoma of the kidney: A case report and review of literature

1 Department of Urology, Hospital de São João, Porto; Department of Urology, Centro Hospitalar do Tâmega e Sousa, Penafiel, Portugal
2 Patology Laboratory Dr. Macedo Dias, Portugal
3 Department of Urology, Military Hospital; Department of Urology, Hospital da Lapa, Portugal
4 Department of Urology, Hospital da Lapa; Medicine Faculty, Porto University, Porto, Portugal
5 Department of Urology, Hospital de São João, Porto; Medicine Faculty, Porto University, Porto, Portugal

Correspondence Address:
Pedro Valente,
Rua Engenheiro Machado Vaz, N 200, Hab. 1.2, 4250 271, Porto
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Source of Support: None, Conflict of Interest: None

Primary mesenchymal chondrosarcoma of the kidney is extremely rare, with only nine cases reported in the English literature. We report a new case of this disease. A 35-year-old man, presented with flank pain, episodic gross hematuria and a painless palpable mass in left abdominal quadrant. Computed tomography scan identified a left renal tumor with 20 cm, with no evidence of regional or metastatic spread disease. The patient underwent radical nephrectomy. The immunohistopathological diagnosis was mesenchymal chondrosarcoma of the kidney. At 18 months of follow-up, there was no evidence of recurrence or distant metastasis. Primary renal chondrosarcoma is so rare that its prognosis is unknown. Disease recurrence is unpredictable and when it is detected, the prognosis is poor. The radical nephrectomy with complete resection of the tumor with wide resection free margins is recommended, and the patients need long-term and close surveillance, with particular attention to local recurrence and uncommon sites of metastization.

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