Home About us Editorial board Ahead of print Current issue Search Archives Submit article Instructions Subscribe Contacts Login 
 
ORIGINAL ARTICLE
Ahead of Print

Association of toll-like receptors with the risk of oral squamous cell carcinoma


1 Department of Oral and Maxillofacial Surgery, The Sixth Affiliated Hospital, Sun Yat sen University, Guangzhou 510655, China
2 Department of Stomatology, Sun Yat sen Memorial Hospital, Sun Yat sen University, Guangzhou, China

Correspondence Address:
Xiang-Bo Kong,
Department of Stomatology, Sun Yat sen Memorial Hospital, Sun Yat sen University, Guangzhou
China
Login to access the Email id

Source of Support: None, Conflict of Interest: None

Aim of Study: Association of toll-like receptors (TLRs) with the risk of oral squamous cell carcinoma (OSCC) from the published reports is still conflicting. This study was conducted to evaluate the relationship between TLRs and the risk of OSCC using meta-analysis method. Materials and Methods: The association studies were identified from PubMed and Cochrane Library on April 01 2015, and eligible investigations were included and synthesized using meta-analysis method. Result: Three reports were recruited into this meta-analysis for the association of TLRs with OSCC susceptibility. In this meta-analysis, we found that TLRs were not associated with OSCC susceptibility. However, in the sub-group analysis, we found that TLR-7 was associated with OSCC risk. Conclusion: TLR-7 was associated with OSCC risk. TLR-7 might be an indicator to predict the OSCC risk. However, more studies should be conducted to confirm it.


Print this article
Search
 Back
 
  Search Pubmed for
 
    -  Fang SL
    -  Kong XB
    -  Zhang ZQ
 Citation Manager
 Article Access Statistics
 Reader Comments
 * Requires registration (Free)
 

 Article Access Statistics
    Viewed318    
    PDF Downloaded17    

Recommend this journal