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Physical activity influences the immune system of breast cancer patients


1 University of Kiel, Comprehensive Cancer Center, University of Kiel, OB/GYN, Breast Unit, Kiel, Germany
2 Department of Obstetrics and Gynecology, University of Kiel, OB/GYN, Breast Unit, Kiel, Germany
3 Institute of Immunology, University of Kiel, Institute of Immunology, Kiel, Germany

Correspondence Address:
Thorsten Schmidt,
University of Kiel, OB/GYN, Breast Unit, Arnold Heller Str. 3, 24105, Kiel
Germany
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Source of Support: None, Conflict of Interest: None

 > Abstract 

It has been suggested that physical activity in breast cancer patients can not only improve quality of life. Influences on physical and psychological levels have been evaluated, but effects on the immune system of breast cancer patients are hardly known. A PubMed search identified relevant trials and meta-analyses from 1970 to 2013. This review summarizes the results of international studies and the current discussion of effects of physical activity on the immune system of breast cancer patients. Highlighted are effects of physical activity on the immune system. Seven original articles and 14 reviews included in this review. Two original and the review articles includes other tumor entities besides breast cancer.Evaluated methods such as dose-response relationships for exercise in oncology, hardly exist. Increased immunological anti-cancer activity due to physical activity is probably mediated via an increase in number and cytotoxicity of monocytes and natural killer cells and cytokines.

Keywords: Breast cancer, immune response, immune system, physical intervention



How to cite this URL:
Schmidt T, Mackelenbergh Mv, Wesch D, Mundhenke C. Physical activity influences the immune system of breast cancer patients. J Can Res Ther [Epub ahead of print] [cited 2017 Apr 25]. Available from: http://www.cancerjournal.net/preprintarticle.asp?id=150356

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