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Year : 2017  |  Volume : 13  |  Issue : 6  |  Page : 1074

Middle East respiratory syndrome virus: Is there any carcinogenicity property?

1 Sanitation 1 Medical Academic Center, Bangkok, Thailand
2 Department of Troical Medicine, Hainan University, Hainan, China

Date of Web Publication13-Dec-2017

Correspondence Address:
Dr. Beuy Joob
Sanitation 1 Medical Academic Center, Bangkok
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/0973-1482.183185

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How to cite this article:
Joob B, Wiwanitkit V. Middle East respiratory syndrome virus: Is there any carcinogenicity property?. J Can Res Ther 2017;13:1074

How to cite this URL:
Joob B, Wiwanitkit V. Middle East respiratory syndrome virus: Is there any carcinogenicity property?. J Can Res Ther [serial online] 2017 [cited 2020 Jul 13];13:1074. Available from: http://www.cancerjournal.net/text.asp?2017/13/6/1074/183185


The Middle East respiratory syndrome (MERS) is a deadly viral infection.[1] The disease cause high mortality. An interesting concern on the causative virus of MERS is the possibility of carcinogenesis. Since MERS is a new disease and there is no long-term clinical data on infected cases, the interesting question is “Is there any carcinogenicity property?” Here, the authors use the bioinformatics technique for predicting. The tool, namely, WAY2DRUG uis used. This tool uses the method, namely, “Prediction of Activity Spectra for Substances technology” in operation.[2] According to the assessment, no carcinogenicity of the MERS virus can be seen in either cancerous and nontumor cell line conditions. Hence, there should be no carcinogenicity property of MERS virus. This finding is concordant with the previous report by Smith et al. that the virus is not a mutagen.[3]

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Conflicts of interest

There are no conflicts of interest.

 > References Top

Joob B, Wiwanitkit V. MERS-CoV. Oman Med J 2014;29:381.  Back to cited text no. 1
Pogodin PV, Lagunin AA, Filimonov DA, Poroikov VV. PASS t argets: Ligand-based multi-target computational system based on a public data and naïve Bayes approach. SAR QSAR Environ Res 2015;26:783-93.  Back to cited text no. 2
Smith EC, Blanc H, Surdel MC, Vignuzzi M, Denison MR. Coronaviruses lacking exoribonuclease activity are susceptible to lethal mutagenesis: Evidence for proofreading and potential therapeutics. PLoS Pathog 2013;9:e1003565.  Back to cited text no. 3


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