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ORIGINAL ARTICLE
Year : 2016  |  Volume : 12  |  Issue : 8  |  Page : 301-303

Does smoking increase the risk of developing glioma? A meta-analysis based on case–control studies


Department of Neurology, Henan University Huaihe Hospital, Kaifeng, Henan, P.R. China

Correspondence Address:
Xiaqing Guo
Department of Neurology, Henan University Huaihe Hospital, Kaifeng, Henan 475000
P.R. China
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0973-1482.200758

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Objective: The purpose of this study was to assess the relationship between smoking and glioma risk by meta-analysis. Materials and Methods: We have searched the databases of MEDLINE, EMBASE, Ovid, and CNKI to find the suitable studies related to association between smoking and glioma risk. The pooled odds ratio (OR) and 95% confidence interval (CI) of smokers in glioma patients compared to normal controls were aggregated by statistic software Stata11.0. The publication bias was evaluated by Begg's funnel plot. Results: Finally, seven case–control studies were included in this meta-analysis. The pooled results showed that smoking did not increase the risk of glioma (OR = 0.96, 95% CI = 0.86–1.07, P > 0.05). Conclusion: No close association between smoking and glioma risk was found in this meta-analysis, which indicate that smoking may not contribute to the incidence of glioma.


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