Home About us Editorial board Ahead of print Current issue Search Archives Submit article Instructions Subscribe Contacts Login 
REVIEW ARTICLE
Year : 2016  |  Volume : 12  |  Issue : 2  |  Page : 464-468

Anesthetics impact on cancer recurrence: What do we know?


1 Department of Anesthesiology, Dr. BRAIRCH, All India Institute of Medical Sciences, New Delhi, India
2 Department of Anesthesiology and Perioperative Medicine, University of Manitoba, Winnipeg, Canada
3 Department of Anesthesiology and Neurological Surgery, Wexner Medical Center, Ohio State University, Columbus, Ohio, USA
4 Department of Anaesthesiology and Intensive Therapy, University of Pecs, Pecs, Hungary

Correspondence Address:
Tumul Chowdhury
Department of Anesthesiology and Perioperative Medicine Health Sciences Center, University of Manitoba, 2nd Floor, Harry Medovy House, 671 - William's Ave., Winnipeg, R3E 0Z2
Canada
Login to access the Email id

Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0973-1482.148670

Rights and Permissions

Surgery is an important component of treatment in cancer patients. However, surgical stress, anesthesia, and perioperative analgesia interfere with the host immune defense mechanisms and may contribute to metastatic dissemination of malignant tumors and cancer progression. Little is known about the effects of anesthesia on tumor recurrence. In vivo studies and clinical data show some evidence that regional anesthesia is beneficial for cancer patients as it may decrease the risk of metastasis. This short review summarizes the clinical data on the possible association between anesthesia, perioperative analgesia, and the risk of cancer recurrence. Most of the clinical reports are based on retrospective studies, and properly designed prospective trials including a sufficient number of patients is required to reveal the interaction of various anesthetic drugs and methods and cancer progression.


[FULL TEXT] [PDF]*
Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)
 

 Article Access Statistics
    Viewed6696    
    Printed169    
    Emailed1    
    PDF Downloaded493    
    Comments [Add]    

Recommend this journal