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Year : 2015  |  Volume : 11  |  Issue : 4  |  Page : 1035

Cerebellar metastases of recurrent phyllodes tumor breast; a rare phenomenon reflecting the unpredictable outcome

1 Department of Pathology, Academic Block, Govind Ballabh Pant Hospital, New Delhi, India
2 Department of Pathology and Laboratory Medicine, All India Institute of Medical Sciences, Bhopal, Madhya Pradesh, India
3 Department of Neurosurgery, Fortis Hospital, Noida, Uttar Pradesh, India

Correspondence Address:
Vineeta Vijay Batra
Department of Pathology, Academic Block, Govind Ballabh Pant Hospital, Jawaharlal Nehru Marg, New Delhi - 110 002
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/0973-1482.154031

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Carcinomas of lung, breast, colon, kidney, and malignant melanomas are the most common malignancies that metastasize to the central nervous system (CNS). Phyllodes tumor is a rare fibroepithelial tumor of the breast, often having unpredictable recurrences, with increasing histological grade and distant metastasis. Malignant forms exist, which may develop distant metastases usually to the lung, pleura, bone, and liver. CNS metastasis of phyllodes tumor is rare and associated with a poor prognosis, with resistance to chemotherapy and radiation. We present a rare case of cerebellar metastasis in recurrent phyllodes tumor breast with subsequent rapid downhill course.

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