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Year : 2015  |  Volume : 11  |  Issue : 4  |  Page : 1025

Unusual presentation of melanoma of unknown primary origin: A case report and review of literature

1 Department of Surgical Oncology, Tata Memorial Centre, Mumbai, Maharashtra, India
2 Department of Molecular Pathology, Tata Memorial Centre, Mumbai, Maharashtra, India

Correspondence Address:
Shailesh V Shrikhande
Department of Surgical Oncology, Gastrointestinal and Hepatopancreatobiliary Service, Tata Memorial Centre, Ernest Borges Marg, Parel, Mumbai - 400 012, Maharashtra
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/0973-1482.148680

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Malignant melanomas often present with metastasis to regional lymph nodes. Patients are also known to present with metastatic nodes in the absence of a known primary. However metastatic melanoma involving the stomach is rare in the scenario of an unknown primary lesion. We present a case of a 41-year-old lady who was treated for nodal disease in the right axilla 8. months earlier with an unknown primary. She later presented to us with a recurrent right axillary swelling and on evaluation was found to also have a nodular deposit on the greater curvature of the stomach. Histopathology of the deposit in conjunction with immunohistochemical markers S.100P, Melan-A and HMB-45, confirmed the diagnosis of malignant melanoma. The patient underwent surgical excision of both lesions and is now on regular follow-up.

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