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Year : 2015  |  Volume : 11  |  Issue : 3  |  Page : 651

Long-term survival in gliosarcoma with radiation-induced meningeal sarcomas: Case report and molecular features

Department of Radiation Oncology, Jinling Hosp, Nanjing Univ Sch Med, Nanjing, China

Correspondence Address:
Xi-Xu Zhu
Department of Radiation Oncology, Jinling Hosp, Nanjing Univ, Sch Med, Nanjing 210002
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/0973-1482.137995

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Gliosarcoma is a rare primary malignant tumor of the central nervous system with poor prognosis. The median survival time of this disease ranges from 6 months to 14.8 months. However, a computer literature search indicated few long-term survivors. We investigated a case of a survivor of gliosarcoma with radiation-induced meningeal sarcomas, who showed no indication of recurrence for more than 9 years. A battery of molecular studies was performed to develop a molecular profile of this unique patient. We also reviewed the distinct clinical and molecular features of the tumor.

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