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Year : 2014  |  Volume : 10  |  Issue : 4  |  Page : 1104-1106

Clear cell sarcoma of the kidney: A case report

1 Department of Pathology, Medical College, Kolkata, India
2 North Bengal Medical College, Siliguri, West Bengal, India

Correspondence Address:
Ayandip Nandi
48/7, Patuapara Lane, P.O. Serampore, Hooghly District, Kolkata - 712 201, West Bengal
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/0973-1482.146106

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Clear cell sarcoma of the kidney is a rare malignant neoplasm of childhood, known for its aggressiveness, its tendency for recurrence, and to metastasize to bone. We report the observation of 8-month-old child presenting with a large abdominal mass. Clinically, it was diagnosed as Wilm's tumor, and left nephrectomy was done. Grossly, 10 cm × 8 cm × 3.5 cm globular, white, encapsulated, smooth mass uniformly involving the whole kidney was noted. Histologically, the tumor was diagnosed as clear cell sarcoma with renal vein showing presence of tumor embolus in lumen. The tumor was given stage-II (NWTS-5 protocol). Immunohistochemistry showed vimentin positive and cytokeratin negative tumor cells. The child is currently undergoing chemotherapy and has not yet shown any sign of bony metastasis.

Abstract in Chinese

肾透明细胞肉瘤:1例报告 摘要 肾透明细胞肉瘤是一种罕见的儿童恶性肿瘤,以其侵袭性,复发的倾向,和骨转移而知名。我们报道一例8个月大的孩子表现为大的腹部巨大包块。在临床上,被诊断为肾母细胞瘤,左肾切除术。大体上,10厘米×8厘米×3.5厘米球状,白色,光滑,质量均匀,有囊包裹,涉及整个肾脏引起了我的注意。组织学上,肿瘤被诊断为肾静脉显示管腔肿瘤栓子透明细胞肉瘤。肿瘤为II期(NWTS 5协议)。免疫组化显示波形蛋白阳性,角蛋白阴性的肿瘤细胞。孩子正在接受化疗,尚未显示出任何骨转移的迹象。 关键词:儿童肾肿瘤,肾透明细胞肉瘤,免疫组化标记

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