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ORIGINAL ARTICLE
Year : 2014  |  Volume : 10  |  Issue : 3  |  Page : 611-617

Analysis of patient specific dosimetry quality assurance measurements in intensity modulated radiotherapy: A multi centre study


1 Radiological Physics and Advisory Division, Bhabha Atomic Research Centre, Mumbai, Maharashtra, India
2 Department of Radiotherapy, P. D. Hinduja Hospital and Medical Research Center, Mumbai, Maharashtra, India
3 Department of Radiotherapy, Basvatarakam Indo American Cancer Hospital and Research Institute, Hyderabad, Andhra Pradesh, India
4 Department of Radiotherapy, Batra Hospital and Medical Research Centre, New Delhi, India, India
5 Department of Medical Physics, Memorial Sloan Kettering Cancer Centre, New York, USA

Correspondence Address:
Rajesh Kumar
Radiological Physics and Advisory Division, Bhabha Atomic Research Centre, CTCRS Building, Anushakti Nagar, Mumbai, Maharashtra
India
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Source of Support: Partially supported by the International Atomic Energy Agency (IAEA), Conflict of Interest: None


DOI: 10.4103/0973-1482.137941

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Aim of the Study: Statistical analysis of pre-treatment dose verification of intensity-modulated radiotherapy (IMRT) fields to assess the quality of the IMRT practice at different radiotherapy centers. Materials and Methods: The dose verification data acquired by the institutional physicist of 10 different hospitals for various types of patients were collected and analyzed for mean, median, standard deviation (SD), range, minimum and maximum % deviation. The percentage of cases having positive and negative dose differences as well dose differences within ± 3% were also determined. Results: The mean values of percentage variation in difference between treatment planning systems calculated dose and difference between measured dose (D TPS and D Meas ) are found to be from – 1.79 to 1.48 and median from – 1.79 to 1.51. The SDs are found to be from 0.76 to 3.70. The range of variation at these centers varies from 3.99 to 16.45 while minimum and maximum values of percentage variation in difference between D TPS and D Meas ranges from – 10.33 to 13.38. The percentage of cases having positive dose difference ranges from 8 to 94 and cases having negative dose difference ranges from 6 to 92. The percentage of cases having dose difference within ± 3% varies from 57 to 100. Conclusion: IMRT centers are having random and biased (skewed towards over or under dose) distribution of the percentage variation in difference between measured and planned doses. The analysis of results of the IMRT pre-treatment dose verification reveals that there are systematic errors in the chain of IMRT treatment process at a few centers. The dosimetry quality audit prior to commissioning of IMRT may play an important role in avoiding such discrepancies.


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