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CORRESPONDENCE
Year : 2014  |  Volume : 10  |  Issue : 1  |  Page : 187-190

A near tetraploid clone in acute myeloid leukemia with CD56 expression


1 Department of Laboratory Medicine, Basavatarakam Indo-American Cancer Hospital and Research Institute, Banjara Hills, Hyderabad, Andhra Pradesh, India
2 Department of Medical Oncology, Basavatarakam Indo-American Cancer Hospital and Research Institute, Banjara Hills, Hyderabad, Andhra Pradesh, India

Correspondence Address:
Sandhya Devi Gundimeda
Department of Laboratory Medicine, Basavatarakam Indo American Cancer Hospital and Research Institute, Road No. 14, Banjara Hills, Hyderabad - 500 034, Andhra Pradesh
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0973-1482.131406

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Acute myeloid leukemia (AML) is a heterogeneous disorder characterized by specific morphology, immunophenotype and genetic rearrangements. Multiple recurrent chromosomal aberrations have been identified by conventional cytogenetic analysis, which are now widely recognized as one of the most important diagnostic and prognostic determinants in AML. Here, we present a case with unusual cytogenetics, which has been described in very few patients.

Abstract in Chinese

一个急性髓细胞性白血病近四倍体克隆与CD56表达 摘要 急性髓细胞白血病(AML)是一种免疫表型和基因重排为特征的异质性疾病。多发的复发性染色体畸变已由传统的细胞遗传学分析发现,这是目前公认的急性髓细胞白血病一个重要的诊断和预后的决定因素。在这里,我们介绍了一个非常少见病人的不寻常细胞遗传学的病例。 关键词:急性髓系白血病,奇特的/大爆炸,CD56的表达,近四倍体



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