Home About us Editorial board Ahead of print Current issue Search Archives Submit article Instructions Subscribe Contacts Login 
Year : 2013  |  Volume : 9  |  Issue : 4  |  Page : 618-623

Influence of the modulation factor on the treatment plan quality and execution time in Tomotherapy in head and neck cancer: In-phantom study

1 Department of Medical Physics, Greater Poland Cancer Centre, Poznan, Poland
2 Department of Medical Physics, Greater Poland Cancer Centre; Department of Electroradiology, University of Medical Sciences, Poznan, Poland

Correspondence Address:
Tomasz Piotrowski
Department of Medical Physics, Greater Poland Cancer Centre, Garbary 15 Street, 61-866 Poznan
Login to access the Email id

Source of Support: None, Conflict of Interest: None

DOI: 10.4103/0973-1482.126458

Rights and Permissions

Purpose: The overall aim was to conduct an analytical study of the impact of the modulation factor (MF) on the quality of the head and neck treatment plans and their execution time on Tomotherapy. Materials and Methods: In-phantom (RANDO® Alderson) planning study of the head and neck cancer was performed. Thirteen different plans in terms of MF were prepared. Other optimization parameters were the same for all plans. Results: Analysis of treatment plans in terms of quality shows that MF < 1.4 does not provide an accepted dose distribution (physician decision). Statistically significant differences were observed for plans with an MF < 1.6. No differences were obtained for plans with MF from 6.0 to 1.8. Decreasing of MF leads to a shorter time of irradiation. The maximum rotational speed has been reached for an MF = 3.0. Further reducing this however produces no decrease in the time of irradiation. The actual and planned values of the MF were compared. The optimal range of MF for head and neck was determined as 3.0 > MF > 1.8. The lower limit increases to 2.4 when hard reduction of the dose in critical organs is required. Conclusions: It was showed that the final MF value is less than the value calculated after each loop of optimization. The computer system reduces MF by shortening the longest time and increasing the average time of leaves opening. Increase in the average time is obtained by eliminating the use of leafs with the shortest times of opening, thereby reducing the dose in critical organs that are outside the direct irradiation area.

Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)

 Article Access Statistics
    PDF Downloaded109    
    Comments [Add]    

Recommend this journal