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CORRESPONDENCE
Year : 2013  |  Volume : 9  |  Issue : 3  |  Page : 532-533

Co-occurrence of diffuse large B cell non-hodgkin lymphoma and chronic hepatitis C in Algerian patients: Two case reports


1 Section of Cancer Information, International Agency for Research on Cancer, 150 Cours A, Thomas, Lyon Cedex, France
2 Department of Internal Medecine, Touhami Benflis University Teaching Hospital, Route de Tazoult, Batna, Algeria
3 Department of Hematology, Touhami Benflis University Teaching Hospital, Route de Tazoult, Batna, Algeria
4 Laboratory of Virology, Hospices Civils de Lyon, Croix Rousse Hospital, 103; U851, Inserm, 103, Grande rue de la Croix-Rousse; University of Lyon, University of Lyon 1, 43, Boulevard du 11 Novembre 1918, Villeurbanne Cedex, Lyon, France
5 University of Lyon, University of Lyon 1, 43, Boulevard du 11 Novembre 1918, Villeurbanne Cedex; Department of Hygiene, Epidemiology and Prevention, Edouard Herriot Hospital, Hospices Civils de Lyon; Laboratory of Epidemiology and Public Health, CNRS, UMR, 5 Place d'Arsonval, Lyon, France

Correspondence Address:
Karima Chaabna
International Agency for Research on Cancer, Cancer Information Section, 150 Cours Albert Thomas, Lyon Cedex
France
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0973-1482.119372

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For the first time in Algeria, we report on the presentation, diagnosis and management of two cases of diffuse large B cell NHL with chronic HCV infection. Both Algerian patients came for medical consult without HCV-related symptoms. Systematic serological tests to identify HIV and hepatitis B and C infections which performed on all patients led to HCV diagnosis. Chemotherapy was given to both patients without exacerbation of the HCV infection. These observed cases shed new light on the possible pathogenesis of NHL in Algerian population. Indeed, in Algeria, HCV may partly been responsible of the unexplained increase of NHL incidence in Eastern region of Algeria especially among those who are frequently exposed to HCV risk factors (haemodialysis and dental care). Furthermore, our observations underscore the importance of prevention programmes including screening to control HCV in Algeria.


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