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CORRESPONDENCE
Year : 2013  |  Volume : 9  |  Issue : 3  |  Page : 484-486

Chronic myeloid leukemia with pregnancy: Successful management of pregnancy and delivery with hydroxyurea and imatinib continued till delivery


1 Department of Obstetrics and Gynaecology, Vardhman Mahaveer Medical College and Safdarjung Hospital, New Delhi, India
2 Department of Anaesthesiology, Critical Care and Pain, Tata Memorial Hospital, Mumbai, India
3 Department of Anaesthesiology, Vardhman Mahaveer Medical College and Safdarjung Hospital, New Delhi, India

Correspondence Address:
Usha Yadav
Department of Obstetrics and Gynaecology, Vardhman Mahaveer Medical College and Safdarjung Hospital, New Delhi
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0973-1482.119305

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The concomitant occurrence of pregnancy and chronic myeloid leukemia is uncommon. We describe the successful management of a 30-year-old G3 P0, A2 woman who was diagnosed to have chronic myelogenous leukemia (CML) in the third trimester of her pregnancy with intra-uterine growth retardation and oligohydroamnios. She was started on hydroxyurea and imatinib, and was continued till delivery and beyond. The use of imatinib did not have any adverse effects on the fetus, except for low birth weight and low APGAR at birth, but the later progress of the child was normal. We conclude that imatinib and hydroxyurea can be continued even at the third trimester in a pregnant lady with CML, if necessary.


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