Home About us Editorial board Ahead of print Current issue Search Archives Submit article Instructions Subscribe Contacts Login 
CORRESPONDENCE
Year : 2013  |  Volume : 9  |  Issue : 2  |  Page : 305-307

Pigmented perivascular epithelioid cell tumor of the liver: Report of a rare case with brief review of literature


1 Department of Pathology, Global Hospital and Health City, Chennai, Tamil Nadu, India
2 Department of Liver Transplantation and Hepatobiliary Surgery, Global Hospital and Health City, Chennai, Tamil Nadu, India
3 Department of Surgical Gastroenterology, Global Hospital and Health City, Chennai, Tamil Nadu, India

Correspondence Address:
Susama Patra
Department of Pathology, Global Hospital and Health City, Chennai - 600 100, Tamil Nadu
India
Login to access the Email id

Source of Support: Nuclear Science and Technology Research Institute (NSTRI), Conflict of Interest: None


DOI: 10.4103/0973-1482.113401

Rights and Permissions

The perivascular epithelioid cell tumor (PEComa) family of tumors includes angiomyolipoma, lymphangioleiomyomatosis, clear cell sugar tumor of the lung, clear cell myomelanocytic tumor of the falciform ligament/ligamentum teres, and rare clear cell tumors of other anatomical sites (PEComas-NOS). Among the PEComas-NOS, pigmented variants are extremely rare. The case concerns a 50-year-old female who presented with pain in right hypochondrium. The resected specimen included a 24 × 18 × 9 cm mass. The tumor was histologically characterized by both spindle and epithelioid cells with round to oval nuclei and clear to eosinophilic cytoplasm containing abundant melanin pigment. The stroma demonstrated intervening, thin, fibrovascular septa. Immunohistochemically, the tumor cells were strongly positive for HMB-45, weak positive for smooth muscle actin (SMA), and negative for Hep Par 1, Glypican 3, MUM-1, and S-100 protein. The patient had no evidence of disease 24 months after surgery. Pathologists and clinicians should know about the existence of pigmented perivascular epithelioid cell tumor of the liver.


[FULL TEXT] [PDF]*
Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)
 

 Article Access Statistics
    Viewed2322    
    Printed77    
    Emailed1    
    PDF Downloaded198    
    Comments [Add]    
    Cited by others 1    

Recommend this journal