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LETTER TO THE EDITOR
Year : 2012  |  Volume : 8  |  Issue : 4  |  Page : 652

Requesting clarifications concerning the case report on 'extraskeletal Ewing sarcoma of the sinonasal tract


1 Department of Radiation Therapy and Oncology, Regional Cancer Centre, Indira Gandhi Medical College, Shimla, India
2 Department of Otolaryngology and Head Neck Surgery, Sultan Qaboos University Hospitals, Muscat, India

Date of Web Publication29-Jan-2013

Correspondence Address:
Priyanka Thakur
Department of Radiation Therapy and Oncology, Regional Cancer Centre, IGMC, Shimla, Himachal Pradesh-171001
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0973-1482.106589

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How to cite this article:
Thakur P, Revannasiddaiah S, Rastogi M, Kumar S. Requesting clarifications concerning the case report on 'extraskeletal Ewing sarcoma of the sinonasal tract. J Can Res Ther 2012;8:652

How to cite this URL:
Thakur P, Revannasiddaiah S, Rastogi M, Kumar S. Requesting clarifications concerning the case report on 'extraskeletal Ewing sarcoma of the sinonasal tract. J Can Res Ther [serial online] 2012 [cited 2019 Sep 20];8:652. Available from: http://www.cancerjournal.net/text.asp?2012/8/4/652/106589

Sir,

Having read the case report titled 'Rare case of extraskeletal Ewing sarcoma of the sinonasal tract' [1] published recently in the Journal of Cancer Research and Therapeutics (JCRT), we seek a few clarifications from the authors. [1]

The authors have assigned the diagnosis as 'extraskeletal' Ewing sarcoma, which in our opinion is questionable. The preoperative computed tomography (CT) image reveals a large soft tissue mass involving the nasal cavity and the paranasal sinuses, with bony erosion of the walls of the maxillary sinus. Thus, there is a likelihood that the tumor could indeed have originated from the bony structures of the region. [2] Skeletal origin is more likely, given the additional fact that only 4-7% of all Ewing sarcomas happen to be 'extraosseous'. [2],[3],[4]

Regarding the choice of chemotherapy, the authors have mentioned 14 cycles of "vincristine, adriamycin, cyclophosphamide and dexamethasone" in the case report. We assume that the authors intended to mean 'd-actinomycin' instead of dexamethasone. However, we would like to know if the chemotherapy was alternative, with cycles of ifosfamide-etoposide.

In addition, it will be appreciated if the authors can kindly shed some light upon the timing, dose, and technique of delivery of radiotherapy, since that would amount to an interesting description regarding the radiotherapy planning of a rare malignancy in a rare site, with abundance of organs at risk in near proximity.

 
 > References Top

1.Yeshvanth SK, Ninan K, Bhandary SK, Lakshinarayana KP, Shetty JK, Makannavar JH. Rare case of extraskeletal Ewings sarcoma of the sinonasal tract. J Cancer Res Ther 2012;8:142-4.  Back to cited text no. 1
    
2.Deshingkar S, Barpande S, Tupkari J. Ewing's sarcoma of zygoma. J Oral Maxillofac Pathol 2009;13:18-22.  Back to cited text no. 2
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3.Hafezi S, Seethala RR, Stelow EB, Mills SE, Leong IT, MacDuff E, et al. Ewing's family of tumors of the sinonasal tract and maxillary bone. Head Neck Pathol 2011;5:8-16.  Back to cited text no. 3
    
4.Javery O, Krajewski K, O'Regan K, Kis B, Giardino A, Jagannathan J, et al. A to Z of extraskeletal Ewing sarcoma family of tumors in adults: Imaging features of primary disease, metastatic patterns, and treatment responses. AJR Am J Roentgenol 2011;197:1015-22.  Back to cited text no. 4
    




 

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