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CORRESPONDENCE
Year : 2012  |  Volume : 8  |  Issue : 4  |  Page : 636-638

Skull-base Ewing sarcoma with multifocal extracranial metastases


1 Department of Neurosurgery, Sri Sathya Sai Institute of Higher Medical Sciences, EPIP Area, Whitefield, India
2 Department of Neuropathology, Sri Sathya Sai Institute of Higher Medical Sciences, EPIP Area, Whitefield, India
3 Department of Neuropathology, National Institute of Mental Health and Neuro Sciences, Bangalore, Karnataka, India

Correspondence Address:
Sumit Thakar
Department of Neurosurgery, SSSIHMS, EPIP Area, Whitefield, Bangalore - 560066
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0973-1482.106584

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Intracranial occurrence of Ewing sarcoma (ES) is unusual, with a skull-base location being anecdotal. We report a 29-year-old man who presented with rapidly progressive ophthalmoplegia, and was found to be harboring an infiltrative lesion involving the sphenoid sinus, sella, and clivus. He underwent trans-sphenoidal decompression of the lesion which was histologically suggestive of ES. He developed paraparesis 2 weeks after commencing adjuvant therapy. Imaging revealed two thoracic extradural lesions and florid vertebral and pulmonary metastases. This is the first report in indexed literature of a primary intracranial ES on the skull-base with disseminated extracranial disease.


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