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REVIEW ARTICLE
Year : 2012  |  Volume : 8  |  Issue : 3  |  Page : 348-354

Irradiation-mediated carbon nanotubes' use in cancer therapy


1 Key Laboratory of Resources Chemistry of Nonferrous Metals, Ministry of Education, Central South University, Changsha, Hunan, China
2 Key Laboratory of Natural Pharmaceutical and Chemical Biology of Yunnan Province, College of Science, Honghe University, Menzi, Yunnan, China

Correspondence Address:
Xiao-Qing Chen
Key Laboratory of Resources Chemistry of Nonferrous Metals, Ministry of Education, Central South University, Changsha, Hunan
China
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Source of Support: Financial supports from the National Natural Science Foundation of China (No. 21201181, 21175155, 21176263), the Research Fund for the Doctoral Program of Higher Education of China (No. 20110162120070), the Planned Science and Technology Project of Hunan Province (No. 2011FJ3175), and the Fundamental Research Funds for the Central Universities (No. 201012200146) are greatly appreciated., Conflict of Interest: None


DOI: 10.4103/0973-1482.103511

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Anticancer drugs such as biological therapeutic proteins and peptides are used for treatment of a variety of tumors. However, their wider use has been hindered by their poor bioavailability and the uncontrollable sites of action in vivo. Cancer nano-therapeutics is rapidly progressing, which is being applied for solving some limitations of conventional drug delivery systems. To improve the bio-distribution of anticancer drugs, carbon nanotubes have been used as one of the most effective drug carriers. This review discusses the carbon nanotubes-mediated methods for the delivery of anticancer drugs, with emphasis on the radiation-induced drug-targeted releasing and selective photo-thermal cancer therapy.


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