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Year : 2012  |  Volume : 8  |  Issue : 1  |  Page : 3-10

Microarrays and cancer diagnosis


Department of Oral Pathology and Microbiology, School of Dental Sciences, Sharda University, Uttar Pradesh, India

Correspondence Address:
Manjul Tiwari
Department of Oral Pathology and Microbiology, D-97, Anupam Apartments, B/13, Vasundhara Enclave, Delhi - 110 096
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0973-1482.95166

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Cancer can be considered a "developmental disorder" because it involves a disruption in the normal development of cells, in terms of both differentiation and proliferation (Dean M,1998). Cancer cells generally contain the full complement of biomolecules that are necessary for survival, proliferation, differentiation, cell death, and expression of cell type-specific function. Human Cancer diagnosis and classification by Microarray analysis has yet to be widely accepted despite the exponential increase in microarray studies reported in the literatures. Additionally, recent microarrays were inspired by the nucleotide-based technology, which have created to better define the molecular basis of malignancy which have shown that microarray have clinical utility in cancer diagnosis, risk stratification, and patient management.


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