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Year : 2012  |  Volume : 8  |  Issue : 1  |  Page : 114-116

Complete response to chemotherapy in primary hepatic lymphoma

1 Department of Hematotology, Sir Ganga Ram Hospital, New Delhi, India
2 Department of Medical Oncology, Sir Ganga Ram Hospital, New Delhi, India
3 Department of Histopathology, Sir Ganga Ram Hospital, New Delhi, India

Correspondence Address:
Mir Sadaqat Hassan Zafar
Department of Hematology, Room No. 3, First Floor, SSRB, Sir Ganga Ram Hospital, New Delhi
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/0973-1482.95187

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Primary hepatic lymphoma is an uncommon lymphoid tumor with varied clinical presentations and treatment outcomes. The median age of involvement is 50 years (male preponderance) with median survival as 8-16 months. Here we report a 68-years-old female who presented with right hypochondriac pain and anorexia with hepatomegaly on physical examination. Ultrasonography (USG) with subsequent contrast enhanced computed tomography (CECT) of abdomen depicted a hypoechoic mass in the left lobe of liver. CECT of chest and neck showed no abnormality. Liver biopsy proved to be Non-Hodgkin lymphoma (NHL) diffuse large B cell type, CD20 positive. Bone marrow examination showed no infiltration by NHL. The patient was started on three weekly R-CHOP, given a total of 8 cycles. Patient attained a complete remission documented by negative computed tomography (CT) and positron emission tomography (PET) scans.

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