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Year : 2011  |  Volume : 7  |  Issue : 4  |  Page : 393-398

Lymphomas: Its gene expression profiling


Department of Oral Pathology and Microbiology, School of Dental Sciences, Sharda University, Uttar Pradesh, India

Correspondence Address:
Manjul Tiwari
Department of Oral Pathology and Microbiology, D-97, Anupam Apartments, B/13, Vasundhara Enclave, Delhi - 110 096
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0973-1482.91998

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To find gene expression patterns in disease and biological processes the use of DNA microarrays has already begun to have a significant impact on modern medicine. Gene expression profiling have impact on hematological malignancies including from prognosis to its therapeutic regimens. DNA microarrays have led to the discovery of better prognostic tools and the mechanisms including molecular of lymphoma have clarified, with a help of cell cycle and DNA damage pathways that are responsible for tumor cell proliferation and different clinical outcomes. While in future it is hope that important discoveries will be done in leukemias, lymphomas, and many other cancer subtypes using gene expression profiling.


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