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CASE REPORT
Year : 2011  |  Volume : 7  |  Issue : 2  |  Page : 192-194

A fatal case of mesenchymal chondrosarcoma of the mandible


1 Department of Surgical Oncology, Cancer Institute (WIA), 36, Sardar Patel Road, Adyar, Chennai-600 020, India
2 Department of Radiation Oncology, Cancer Institute (WIA), 36, Sardar Patel Road, Adyar, Chennai-600 020, India
3 Department of Pathology, Cancer Institute (WIA), 36, Sardar Patel Road, Adyar, Chennai-600 020, India

Correspondence Address:
Arvind Krishnamurthy
Department Surgical Oncology, Cancer Institute (WIA), 36, Sardar Patel Road, Adyar, Chennai-600 020
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0973-1482.82919

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A 34-year-old man presented with an expansile, erosive tumor involving the left side of the mandible, with secondary invasion into the maxilla, measuring 13 Χ 7 cm. Microscopic analysis revealed a malignant small round cell neoplasm with focal cartilaginous differentiation. Immunohistochemical analysis revealed positivity for vimentin, NSE and CD99 with primitive small round cells, and S100 positivity with neoplastic chondrocytes. To the best of our knowledge, this is perhaps the largest reported case of mesenchymal chondrosarcoma of the maxillofacial region. Diagnosed as inoperable, he was treated with radiation and chemotherapy only to die within a few months.


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