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Journal of Cancer Research and Therapeutics
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Year : 2011  |  Volume : 7  |  Issue : 1  |  Page : 81-83

Muscle metastasis from hepatocellular carcinoma

1 Department of Oncology, Aretaieion University Hospital, 76 V. Sofias 11528, Athens, Greece
2 Radiology Department, Kapodistrian, University of Athens, Athens, Greece
3 Laboratory Forensic Medicine and Toxicology, Evgenidion Hospital University of Athens, 76 V. Sofias 11528, Athens, Greece

Correspondence Address:
Anna Zygogianni
Department of Radiology, Aretaieion Hospital, University of Athens, 76 V. Sofias, 11528, Athens
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DOI: 10.4103/0973-1482.80467

PMID: 21546750

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Background: Hepatocellular carcinoma is the most common primary tumor of the liver. Disease dissemination occurs through hematogenous routes and frequently involves the lungs, bone, adrenal glands, and pancreas. The patterns of the extrahepatic manifestations are diverse. Soft tissue metastasis is extremely rare and mandates systematic pathological analysis, which may include the use of specific immunohistochemical staining. We report metastasis from a hepatocellular carcinoma, as a discrete subcutaneous mass to the right humerus muscle. Materials and Methods: We detail the approach to diagnosis and management of an unusual case of a patient with hepatocellular carcinoma, in whom we found a metastatic lesion as a subcutaneous mass to the right humerus muscle nine years after right hepatectomy. Conclusion: This condition poses differential diagnostic problems in the settings of clinical and pathological investigations. Metastasis of hepatocellular carcinoma should be included in the differential diagnosis of rapidly growing lesions.


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