| CASE REPORT |
|
| Year : 2010 | Volume
: 6
| Issue : 1 | Page : 89-91 |
Late solitary testicular metastasis from rectal cancer
Ramachandran Venkitaraman1, Mathew George2, Suranga Weerasooriya3, Sid Selva-Nayagam4
1 Ipswich Hospital NHS, United Kingdom
2 Department of Medical Oncology, Tamworth Hospital, Australia
3 Department of Medical Oncology, Royal Darwin Hospital, Darwin, NT, 0810, Australia
4 Royal Adelaide Hospital, Australia
Correspondence Address:
Mathew George
Department of Medical oncology, Tamworth Hospital, New South Wales
Australia
DOI: 10.4103/0973-1482.63562 PMID: 20479555
Isolated testicular metastasis from rectal cancer is rare. We describe the case of a patient who presented with a locally advanced rectal malignancy and underwent multimodality treatment with low anterior resection, postoperative radiotherapy and adjuvant chemotherapy. He developed a painless testicular nodule while on follow-up, five years after the diagnosis of primary rectal cancer. Histopathology and immunohistochemistry of orchidectomy specimen were compatible with a metastatic adenocarcinoma of rectal origin. We hypothesize that this phenomenon of isolated relapse in a sanctuary site could be due to the altered biology and pattern of metastasis as a result of effective adjuvant systemic chemotherapy. Treatment of late isolated relapse in the testis needs to be ascertained.
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